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Between-group comparisons for pooled placebo-controlled trials in adults revealed no statistically significant differences between risperidone and placebo in mean changes from baseline in risperdal ECG parameters, including QT, QTc, and PR intervals, and heart rate . When all risperdal RISPERDAL� doses were pooled from randomized controlled trials in several indications, there was a mean increase in heart rate of 1 beat per minute compared to no change for placebo patients . In pooled placebo-controlled acute mania trials in adults, there were small decreases in mean heart rate, similar what is risperdal consta risperdal class action lawsuit johnson and johnson lawsuit risperdal among all treatment groups . In short-term risperdal pharmaceutical company does risperdal make you gain weight johnson and johnson risperdal schizophrenia trials, higher doses of risperidone (8-16 mg/day) were associated with a higher mean increase in heart rate compared to placebo (4-6 beats per minute) .
Table 10: Adverse Reactions in ? 2% of RISPERDAL�-Treated Adult Patients (and greater than risperdal placebo) with Bipolar Mania in Double-Blind, Placebo-Controlled Monotherapy Trials .
The adverse reactions associated with discontinuation in more than risperdal one RISPERDAL�-treated pediatric patient were nausea (3%), somnolence (2%), sedation (2%), and vomiting (2%) . In risperdal a double-blind, placebo-controlled trial 12% (13/111) of RISPERDAL�-treated patients discontinued due to an adverse reaction, compared with 7% (4/58) of placebo-treated patients .
Adverse Reaction RISPERDAL� 1-6 risperdal mg/day .
Similar methods were used to measure extrapyramidal symptoms (EPS) in risperdal an 8-week trial comparing 5 fixed doses of RISPERDAL� (1, 4, 8, 12, and 16 mg/day): .
RISPERDAL� + Mood risperdal Stabilizer .
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